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Safety And Efficacy Of Oral Administered Cepharanthine In Non-Hospitalized, Asymptomatic Or Mild COVID-19 Patients: A Double-Blind, Randomized, Placebo-Controlled Trial

research Safety and efficacy of oral administrated cepharanthine in non-hospitalized, asymptomatic or mild COVID-19 patients: a Double-blind, randomized, placebo-controlled trial

3 citations , January 2025 in “Scientific Reports”

This study found that treating asymptomatic or mild COVID-19 with cepharanthine did not significantly reduce the time to a negative test result, though 60 mg/day showed a non-significant trend needing further validation.

Safety and Efficacy of Orally Administered Cepharanthine in Non-Hospitalized, Asymptomatic or Mild COVID-19 Patients: A Double-Blind, Randomized, Placebo-Controlled Trial

research Safety and Efficacy of Oral administrated Cepharanthine in Non-hospitalized, asymptomatic or mild COVID-19 patients: A Double-blind, Randomized, Placebo-controlled Trial

1 citations , January 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

In this study, 60 mg/day of Cepharanthine significantly reduced the time to a negative COVID-19 test among de novo infected patients with good compliance, though 120 mg/day showed no such effect.

research Seventeen Cases of Alopecia Areata: Combination of SADBE Topical Immunotherapy with Other Therapies

36 citations , October 2002 in “The Journal of Dermatology”

This study suggests that combining topical squaric acid dibutylester with other therapies may improve hair regrowth in patients with alopecia areata unresponsive to topical therapy alone.

research Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19

70 citations , July 2020 in “Pharmacological Reports”

This review discusses the antiviral potential of cepharanthine against SARS-CoV-2, noting its effectiveness in preclinical models but presenting no new clinical results.

research Bioavailability Enhancement of Cepharanthine via Pulmonary Administration in Rats and Its Therapeutic Potential for Pulmonary Fibrosis Associated with COVID-19 Infection

14 citations , April 2022 in “Molecules”

This study found that pulmonary delivery of cepharanthine significantly improved bioavailability and may provide protective effects against pulmonary fibrosis related to COVID-19 infection in a rat model.

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Learn

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learn Cepharanthine

learn Finasteride

Topical or oral? Choosing between pills and lotions according to your case. Topical finasteride offers localized treatment with fewer systemic side effects than oral finasteride.

learn Metformin

Is metformin used topically for hair loss, or only as an oral tablet? Approved metformin products are oral tablets only; there is no approved topical metformin for hair loss. Published human reports of topical use are a handful of uncontrolled, pharmacy-compounded case reports in scarring alopecia, and the most-cited clinical series actually used the oral drug.

learn Sulforaphane

Is sulforaphane used in oral supplements or topical hair treatments? Sulforaphane is primarily used in oral supplements, not topical hair treatments.

learn white tea

Is white tea more effective in topical hair products or as an oral supplement for hair growth? Neither topical nor oral white tea has any human clinical trial behind it for hair growth. Topical use has a more direct mechanistic rationale, but the only verifiable studies are a cell-culture EGCG experiment and a pharmacokinetic study with no hair outcomes.

learn Estradiol

How does topical Estradiol compare to oral Estradiol in treating alopecia? Topical estradiol delivers hormone to the scalp with less systemic exposure, but evidence is thin and it is still a hormone. It needs a doctor's supervision, and people with estrogen-sensitive cancers must not use it without medical approval.

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Community Join

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community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

29 upvotes 12 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

community Does oral min cause body/facial hair growth if I don't have much body/facial hair to begin with?

1 upvotes 15 hours ago

Oral minoxidil can cause body and facial hair growth, even if you have little hair to begin with. The user is considering oral and topical minoxidil for hair preservation, with advice to use both and not stop oral DHT blockers like finasteride.

community How much does oral minoxidil and finsteride cost you?

1 upvotes 1 day ago

Oral minoxidil and finasteride costs vary, with some users reporting $18 for 90 days of finasteride and $31 for 90 days of minoxidil through Amazon. Splitting higher-dose pills can reduce costs to $20-40.

community Facial bloating/aging on oral Min

4 upvotes 4 days ago

Oral minoxidil can cause facial bloating, leading to a puffy appearance. Some users report improvement after stopping the medication.

community Oral Fin to Dut switch, Libido Change timeline?

4 upvotes 4 days ago

The user switched from oral finasteride to dutasteride due to libido issues and is seeking advice on the timeline for libido recovery and potential hair gains. Some users suggest exercise to alleviate side effects, while others discuss the rarity of sexual side effects and recommend switching back to finasteride if issues persist.

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