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Oral Testosterone in Oil: Pharmacokinetic Effects of 5α-Reduction by Finasteride or Dutasteride and Food Intake in Men

research Oral Testosterone in Oil: Pharmacokinetic Effects of 5 Reduction by Finasteride or Dutasteride and Food Intake in Men

22 citations , January 2006 in “International Journal of Andrology”

This study found that coadministration of 5α-reductase inhibitors with oral testosterone in oil significantly increases serum testosterone levels in medically castrated men compared to testosterone alone, with food intake minimally affecting these levels.

research 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia

June 2001 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology”

This review discusses advances in 5α-reductase inhibitors for treating male androgenetic alopecia and reports no new clinical results.

research Current and Emerging Approaches to Androgenetic Alopecia

January 2026 in “Dermatology Review”

This review discusses androgenetic alopecia, outlining its genetic and hormonal causes, and summarizes current and emerging treatments like minoxidil, finasteride, and low-dose oral therapies, emphasizing the need for more research to confirm the efficacy and safety of newer approaches.

Male Androgenetic Alopecia: Medical and Surgical Treatments

research Male androgenetic alopecia (Part II)

9 citations , February 2005 in “The Journal of Men's Health & Gender”

This article reviews treatment options for male androgenetic alopecia, including their distinct aims of arresting progression, stimulating regrowth, and concealing hair loss, and reports no new clinical results.

research Frontal fibrosing alopecia: efficacy of treatment modalities

14 citations , April 2019 in “International Journal of Women's Health”

This review highlights current treatment options for frontal fibrosing alopecia, noting that 5-α-reductase inhibitors, intralesional steroids, and hydroxychloroquine have the highest evidence of effectiveness, while other therapies show variable results and need further research.

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Community Join

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community Been taking fin oral for 2 years no regrowth. Can I add DUT 1x per week?

in Finasteride/Dutasteride 4 upvotes 1 month ago

OP has been taking oral finasteride for 2 years with no regrowth and is considering adding dutasteride once a week but is concerned about potential side effects. Users suggest adding dutasteride multiple times a week and using minoxidil for better results.

community 3 months progress (1mg oral fin + 2.5 mg oral min)

21 upvotes 4 months ago

A 33-year-old male shared his 3-month progress using 1mg oral finasteride and 2.5mg oral minoxidil, along with supplements and serums, reporting thicker hair and new growth in thinning areas without side effects. Users suggested considering dutasteride or a hair transplant for better results, while others encouraged continuing the current regimen for at least a year.

community So does oral minoxidil age your skin or not

43 upvotes 2 years ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community Topical dutasteride significantly outperforms oral finasteride

in Research/Science 65 upvotes 11 months ago

Topical dutasteride 0.05% is reported to outperform oral finasteride with minimal side effects, but concerns about study bias exist due to company funding. Some users report mixed results with topical dutasteride, noting issues with skin penetration and systemic absorption.

community Finasteride, dutasteride, and oral min- My experience

in Finasteride/Dutasteride 126 upvotes 5 years ago

User took Fin for 3 years, Dut for 7 months, and oral Min for 2 months without side effects. Fin stopped hair loss for 2 years, Dut maintained hair, and oral Min regrew thinning hair.

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Learn

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learn retinoic acid

learn RU58841

a potent but unapproved and potentially problematic topical anti-androgen

learn Minoxidil

An essential vasodilator with some anti-androgenic effects

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