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      learn Rosemary

      herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties

      learn Hydrocortisone

      a synthetic cortisol used for anti-inflammatory effects

      learn Rapamycin

      mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

      learn Osteopontin

      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

    Research

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      PP405 Identity Research

      community PP405 Identity Research

      in Research  292 upvotes 5 months ago
      PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  742 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  7 upvotes 2 years ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

      community Rosemary oil works. I definitely does

      in Treatment 3 weeks ago
      Rosemary oil is claimed to slow hair loss and improve hair thickness, but its effectiveness is debated, with some users preferring proven treatments like minoxidil and finasteride. Lifestyle factors and consistent use are suggested to enhance results, though skepticism about natural remedies remains.