19 citations
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January 2020 in “Journal of Biophotonics” This study found that using a PEG-400/oleic acid mixture as an optical clearing agent enhanced the detection depth of particles in skin without causing dehydration, based on tests in rats and further testing in vivo.
2 citations
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June 2020 in “Journal of Investigative Dermatology” This article reviews the steps and methods involved in preparing skin tissues for three-dimensional volumetric imaging, highlighting its potential to provide detailed insights into skin structure not possible with traditional 2D histology, but reports no new findings.
1 citations
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October 2010 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study found that while short-term use of PEG-400 and Thiazone affected rat skin structure, the changes were reversible with no long-term effects observed.
August 2018 in “Journal of Investigative Dermatology” This study found that combining optical clearing methods with light-sheet fluorescence microscopy allows detailed 3D visualization of normal and pathological human skin biopsies, revealing differences in epidermal thickness and volume.
December 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” This review covers various dermatological studies, including findings on glycerol's optical clearing effects, approaches to keloid prevention, itch quantification, baldness heritability, and fumaric acid esters for psoriasis, without presenting new clinical results.