research Sex Differences in Opioid-Mediated Effects: Role of Androgens
Men and women react differently to opioids, with hormones potentially influencing these differences.
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5 / 443 results research An Exploratory Analysis of 5-Alpha Reductase Inhibitors and Risk of Opioid Use Disorder Among Male Medicare Beneficiaries Receiving Prescription Opioid Medications
Using 5-alpha reductase inhibitors may lower the risk of opioid addiction in men taking opioids.
research An Overlooked Sequela of Long-Term Opioid Analgesic Use: A Case Report on Central Adrenal Insufficiency
Long-term opioid use can cause a serious condition where the adrenal glands don't work properly, which doctors should watch out for.
research Cutaneous Manifestations Associated With Substance Use Disorders
Skin issues can signal substance use, helping early detection and treatment.
research The 5α-Reductase Inhibitor Finasteride Reduces Opioid Self-Administration in Animal Models of Opioid Use Disorder
Finasteride reduces opioid use and withdrawal symptoms in animals.
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5 / 25 resultscommunity How uninformed the general public is about hair loss
The conversation highlights the general public's lack of knowledge about hair loss, with various ineffective remedies suggested, such as not wearing hats or using hair fibers. The only effective treatments mentioned for male pattern baldness are medications like minoxidil and finasteride, and hair transplants.
community 11 months of finasteride use, but side effects are becoming increasingly real
A user experienced severe sexual side effects and man boobs after 11 months of finasteride use, despite initial positive results for hair growth. They are discontinuing finasteride and caution others about potential risks, suggesting that side effects may be more common than reported.
community Just passed by a homeless guy!
Hair loss treatments include finasteride, minoxidil, alfatradiol, vitamins, red light therapy, ketoconazole shampoo, meditation, green tea, leg workouts, and silk pillows. Genetics is emphasized as the primary factor in hair health, with some humor about unconventional methods like drug use affecting hair loss.
community So we’re just ok with taking a research chemical now?
The conversation discusses the use of RU58841, a non-FDA approved research chemical for hair loss, with mixed opinions on its safety and effectiveness. Some users are willing to try it as a last resort after other treatments like Minoxidil and Finasteride failed, while others express concerns about potential long-term side effects and lack of official research.
community Sugar and Hair loss connections
High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.