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research Expanding Phenotype of Hereditary Fibrosing Poikiloderma with Tendon Contractures, Myopathy, and Pulmonary Fibrosis Caused by FAM111B Mutations: Report of an Additional Family Raising the Question of Cancer Predisposition and a Short Review of Early-Onset Poikiloderma

23 citations, March 2017 in “JAAD case reports”

The document suggests a possible link between FAM111B gene mutations and increased cancer risk, particularly pancreatic cancer.

The TFIID Subunit TAF4 Regulates Keratinocyte Proliferation and Has Cell-Autonomous and Non-Cell-Autonomous Tumor Suppressor Activity in Mouse Epidermis

research The TFIID Subunit TAF4 Regulates Keratinocyte Proliferation and Has Cell-Autonomous and Non-Cell-Autonomous Tumor Suppressor Activity in Mouse Epidermis

28 citations, July 2007 in “Development”

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

research Ornithine Decarboxylase Expression Leads to Translocation and Activation of Protein Kinase CK2 In Vivo

52 citations, May 1997 in “Journal of Biological Chemistry”

High ornithine decarboxylase levels may lead to hair loss and cancer by increasing CK2 activity in the nucleus.

research The Complex Relationship Between TFEB Transcription Factor Phosphorylation and Subcellular Localization

344 citations, May 2018 in “EMBO journal”

Phosphorylation controls TFEB's location in the cell, affecting cell metabolism and stress response.

research Revising the Role of the Androgen Receptor in Breast Cancer

68 citations, April 2014 in “Journal of Molecular Endocrinology”

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

View more "oncogenic activity" in research →

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community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community Physician here AMA – 30M oral Fin 1-1.25 mg daily

in Update 47 upvotes 2 years ago

Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.