This study found that nestin-expressing cells in the hair follicle bulge exhibit multipotent stem cell-like properties and can generate neural cells both in vitro and in vivo.
25 citations
,
January 2015 in “World journal of stem cells”
This review discusses the potential of hair follicle stem cells as a novel source for cell therapy in neurodegenerative disorders, but it reports no new clinical results.
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”
This study found that Cannabidivarin (CBDV) promotes neuronal survival, proliferation, and differentiation via TRPV1 activation but inhibits oligodendrocyte differentiation in postnatal neurogenesis.
2 citations
,
October 2023 in “Philosophical Transactions of the Royal Society B Biological Sciences”
This study identified novel isoforms of the PADI2 and PADI3 proteins, showing that PADI2β inhibits oligodendrocyte differentiation, possibly by opposing the effect of canonical PADI2, while PADI3β modulates the activity of PADI3α, suggesting new regulatory mechanisms of citrullination in tissue development.