research Valproic acid and/or rapamycin preconditioning protects hair follicle stem cells from oxygen glucose serum deprivation-induced oxidative injury via activating Nrf2 pathway.
In this study, preconditioning hair follicle-derived stem cells with valproic acid and/or rapamycin was shown to protect against damage caused by oxygen glucose and serum deprivation, potentially enhancing stem cell therapy efficacy for ischemic stroke by improving cell adaptation to oxidative stress.