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This case study suggests that long-term treatment with buprenorphine/naloxone for opioid addiction may lead to secondary adrenal insufficiency, warranting further investigation.

This clinical case report identifies xanthomatous hypophysitis in a male patient, highlighting the mismatch between clinical symptoms and MRI findings, which led to a pituitary biopsy and accurate diagnosis instead of unnecessary surgery.

This case report highlights the diagnostic challenge of identifying androgen-secreting ovarian Leydig cell tumors in postmenopausal women when imaging fails to reveal masses, emphasizing the usefulness of ovarian vein sampling for localization.

This case study reports a rare instance of an estradiol-secreting adrenocortical carcinoma in a 58-year-old male, causing feminization and Marie-Antoinette syndrome, with potential paraneoplastic aortitis.

This case study suggests that genetic susceptibility to PCOS and rare syndromes, such as Trichorhinophalangeal syndrome Type 1, should be considered in young men with unexplained hyperandrogenism.