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This study found that the Wnt pathway activator lithium chloride promotes proliferation and odontoblast differentiation of hair follicle neural crest cells.

This study found that overexpression of the transcription factor NFIC may enhance the proliferation and differentiation of stem cells from the apical papilla, suggesting its potential role in dentin/root regeneration.

This study found that Wnt10a expression in odontoblasts increased with dental pulp regeneration and may be a potential non-cellular agent for inducing dental pulp regeneration with dentine-inducing capacity.

This study found that mesenchymal cells from adult mouse whisker follicles differentiated into odontoblast-like cells, demonstrating odontogenic potential in a specialized microenvironment both in vitro and in vivo.

In this study, the researchers found that thymosin beta-4 promotes odontoblastic differentiation in human dental pulp cells, suggesting it as a potential mechanism for regenerative endodontics.