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Neonatal Finasteride Administration Decreases Dopamine Release in Nucleus Accumbens After Alcohol and Food Presentation in Adult Male Rats

research Neonatal Finasteride Administration Decreases Dopamine Release in Nucleus Accumbens After Alcohol and Food Presentation in Adult Male Rats

3 citations, August 2016 in “Behavioural Brain Research”

Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.

research Exploring the Neural Mechanisms of Finasteride: A Proteomic Analysis in the Nucleus Accumbens

14 citations, October 2016 in “Psychoneuroendocrinology”

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

research Hedonic Sensitivity to Natural Rewards Is Affected by Prenatal Stress in a Sex-Dependent Manner

28 citations, May 2015 in “Addiction Biology”

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

research Steroid 5α-Reductase 2 Deficiency Leads to Reduced Dominance-Related and Impulse-Control Behaviors

14 citations, February 2018 in “Psychoneuroendocrinology”

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

research Targeting Neurosteroid Synthesis as a Therapy for Schizophrenia-Related Alterations Induced by Early Psychosocial Stress

24 citations, May 2015 in “Schizophrenia Research”

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

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community Does melatonin dissolve in isopropyl alcohol

in Technology 6 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Do hair follicles ever really "die"? Or does all your front, mid, and crown hair just become vellus?

in Chat 139 upvotes 3 months ago

Hair follicles don't truly die but become severely miniaturized. Treatments like finasteride, dutasteride, and minoxidil can help restore hair by providing nutrients and reducing harmful effects on hair roots.

community This Is A Minoxidillo. Could It Hold The Key To Solving Hair Loss?

in Satire 377 upvotes 1 year ago

The conversation is about different treatments for hair loss, including minoxidil, finasteride, RU58841, macroneedling, and pyrilutamice.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community 2.5 yrs progress: Min + dermaroll + niz

in Progress Pictures 76 upvotes 1 year ago

A user's 2.5 year hair loss progress with Minoxidil, dermarolling, and Nizoral treatments, as well as taking biotin and a multivitamin supplement, with the intention of trying DIY topical finasteride in the future.

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