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All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

research All Roads Lead to the Nucleus: Integration of Signaling, Transcription Factor-Mediated, and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration

January 2018 in “Stem cell biology and regenerative medicine”

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

research Analysis of Bimatoprost-Induced Changes on Rabbit Eyelash Follicle: Clinical and Electron Microscopic Study

1 citations, December 2019 in “Clinical ophthalmology”

Bimatoprost eye drops make rabbit eyelashes longer, thicker, and darker, and increase the number of lashes without causing inflammation.

research Association Between Human Hair Loss and the Expression Levels of Nucleolin, Nucleophosmin, and UBTF Genes

5 citations, February 2016 in “Genetic Testing and Molecular Biomarkers”

Hair loss is significantly linked to lower levels of certain genes in hair follicles.

research Thu646 Postmenopausal Hyperandrogenism Secondary To Ovarian Leydig Cell Tumor

October 2023 in “Journal of the Endocrine Society”

A woman's increased facial hair and hair loss were caused by a rare ovarian tumor, cured by surgery.

research Novel Splicing-Site Mutation in DCAF17 Gene Causing Woodhouse-Sakati Syndrome in a Large Consanguineous Family

4 citations, December 2021 in “Journal of clinical laboratory analysis”

A new mutation in the DCAF17 gene was found to cause Woodhouse-Sakati syndrome in a large family.

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community Does melatonin dissolve in isopropyl alcohol

in Technology 8 upvotes 2 years ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Breezula phase 3 results said to be released next month

in Product 30 upvotes 2 months ago

Breezula's phase 3 results are expected soon, with discussions on the effectiveness of androgen receptor antagonists like spironolactone and the potential of GT20029. Users express skepticism about new treatments and discuss the complexities of male pattern baldness, often relying on finasteride despite its side effects.

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