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research Androgen binding profiles of two distinct nuclear androgen receptors in Atlantic croaker (Micropogonias undulatus)

58 citations , June 2000 in “The Journal of Steroid Biochemistry and Molecular Biology”

This study found that Atlantic croaker nuclear androgen receptors AR1 and AR2 have different binding affinities for androgens, suggesting that they may mediate distinct physiological actions in teleosts.

research Side gland of Suncus murinus as a new model of sebaceous gland: 5?-reductase, androgen receptor, and nuclear androgen content in male and female animals

7 citations , January 1989 in “Archives of Dermatological Research”

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

research Nuclear and cytosol Androgen Receptor in Androgen Dependent Dermatoses in Female Patients

5 citations , July 2009 in “Experimental and Clinical Endocrinology & Diabetes”

This study found that nuclear androgen receptor levels varied among females with androgen-dependent dermatoses, being highest in hirsutism, which may suggest superior androgen stimulability compared to acne and androgenetic alopecia.

research Detection of the nuclear translocation of androgen receptor using quantitative and automatic cell imaging analysis

December 2024 in “Tissue and Cell”

In this study, researchers developed a method to automatically detect androgen receptor nuclear translocation in dermal papilla cells using fluorescence markers and image analysis, finding that the receptor's nuclear signal peaks about 20 minutes after DHT exposure.

research Activation of nuclear factor κB in response to cream ingestion is related to ovarian androgen hypersecretion in polycystic ovary syndrome

6 citations , August 2013 in “Fertility and Sterility”

This study found that cream ingestion increased NFκB activation in women with PCOS, which was associated with insulin resistance and higher ovarian androgen levels, regardless of obesity status.

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Community Join

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community Wouldn’t this nuclear stack make it almost impossible to lose hair?

67 upvotes 1 year ago

The conversation discusses a hair loss treatment regimen involving dutasteride, pyrilutamide, oral minoxidil, and microneedling, with the aim of suppressing DHT and stimulating hair growth. Users debate the effectiveness and potential side effects of these treatments, noting that individual results may vary and that no treatment is foolproof.

community ultimate nuclear stack? need more suggestions bruhh

in Technology 2 upvotes 1 year ago

The conversation discusses an extensive hair loss treatment regimen including dutasteride, GT20029, RU58841, pyrilutamide, minoxidil, microneedling, ketoconazole shampoo, and experimental compounds. The user humorously describes their approach as a comprehensive strategy to combat hair loss while maintaining hair growth.

community What would an actual nuclear stack look like?

42 upvotes 4 months ago

The conversation discusses various treatments for hair loss, including high doses of dutasteride, oral minoxidil, RU58841, microneedling, ketoconazole shampoo, and other supplements like pumpkin seed oil and multivitamins. It also touches on more extreme measures like estrogen therapy and castration, with some users emphasizing the importance of overall health and nutrition.

community My nuclear skitzo hairloss stack

6 upvotes 7 months ago

The conversation discusses a hair loss treatment regimen involving high doses of dutasteride, finasteride, and minoxidil, with concerns about safety and potential side effects. Users advise against the excessive use of these medications, suggesting more moderate approaches and consulting a doctor.

community Feeling hopeless even on nuclear stack

25 upvotes 7 months ago

The user feels hopeless about hair loss despite using finasteride, dutasteride, minoxidil, and RU58841, and having a hair transplant. They are advised to maintain consistency in treatment, consider increasing dutasteride dosage, and explore topical solutions for better results.

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Learn

4 / 801 results

learn Metformin

diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

learn Cyproterone

a synthetic anti-androgen and weak progestogen that inhibits DHT binding to androgen receptor

learn Pyrilutamide

highly targeted anti-androgen that might have minimal systemic effects

learn Alfatradiol

a synthetic estrogen used topically as an anti-androgen

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