260 citations
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January 2020 in “Nature” Stress can cause hair to turn gray by depleting stem cells.
123 citations
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May 2009 in “Journal of Neuroscience” In this study, researchers found that in late pregnancy, the neuroactive progesterone metabolite allopregnanolone inhibits HPA axis responses to immune challenges via an opioid-mediated mechanism.
7 citations
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January 2020 in “Nature” This study found that stress-induced signaling from the sympathetic nervous system in mice led to the depletion of stem cells in hair follicles, resulting in premature greying.
5 citations
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March 2016 in “Medical journal, Armed Forces India” This report describes a case of refractory shock and pulmonary edema resulting from the accidental ingestion of topical minoxidil, highlighting a rare instance of poisoning.
4 citations
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August 2021 in “Frontiers in Cell and Developmental Biology” This review discusses recent advancements in understanding how the sympathetic nervous system and norepinephrine regulate hair follicle growth, highlighting innovative studies that explore their effects on hair follicle stem cells.