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research An Uncommon Presentation of Tumid Lupus Erythematosus Manifesting As Annular, Non-scarring Alopecia on the Scalp

January 2025 in “Cureus”

This case report highlights that tumid lupus erythematosus should be considered in the differential diagnosis of annular scalp lesions with non-scarring alopecia, emphasizing histopathological examination for accurate diagnosis.

research Alopecia areata-like patchy non-scarring alopecia as an initial presentation of systemic lupus erythematosus

3 citations , December 2022 in “Rheumatology Advances in Practice”

This case study reported that systemic lupus erythematosus (SLE) can initially present as patchy non-scarring alopecia, potentially misdiagnosed as alopecia areata, highlighting the importance of thorough examination.

An Atypical Clinical Presentation of Alopecia in Two Patients with Systemic Lupus Erythematosus

research An atypical clinical presentation of alopecia in 2 patients with systemic lupus erythematosus

3 citations , October 2019 in “JAAD Case Reports”

This review discusses different forms and patterns of alopecia associated with lupus erythematosus and reports no new clinical results; the authors highlight distinct features of these conditions.

research A Case of Linear Alopecia of the Scalp

1 citations , January 2020 in “Skin Appendage Disorders”

Treatment with methotrexate and prednisolone led to complete hair regrowth and no relapse for 2 years.

research Geometric alopecia associated with lupus erythematosus panniculitis of the scalp: a case series of nine Korean patients

2 citations , May 2018 in “European Journal of Dermatology”

Lupus erythematosus panniculitis on the scalp can cause unique geometric hair loss patterns.

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community Insane shed 3 months on Fin + Min Oral

88 upvotes 3 months ago

The user experienced severe hair shedding after starting oral Minoxidil and Finasteride, possibly due to stress from a breakup. Many suggest the shedding resembles alopecia areata and recommend seeing a doctor immediately.

community Quote from Pelage (PP-405) Spokesperson...

122 upvotes 10 months ago

Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

community 2/3 non response rate to pp405?

10 months ago

PP405 showed 31% regrowth in a short trial, but its effectiveness is debated compared to Minoxidil and Finasteride. Some argue AGA isn't scarring, while others believe it leads to fibrosis, affecting treatment outcomes.

community Sexual Dysfunction in Those with Androgenetic Alopecia on Dutasteride Versus Finasteride

in Finasteride/Dutasteride 113 upvotes 1 year ago

Dutasteride and finasteride have similar risks of sexual dysfunction for treating androgenetic alopecia. Users experience varying side effects, indicating individual differences in drug reactions.

community Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men

26 upvotes 4 years ago

N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.

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learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn GHK-Cu

Heard alopecia areata leaves scar-like spots? Some peptides are helping those areas regrow hair. Alopecia areata patches usually still have living follicles. Peptides are being studied as a possible add-on, but the evidence is small and early. See a dermatologist for treatment.

learn PP405

Got small bald patches they say are from stress? PP405 sprays could help bring them back to life. PP405 is an experimental topical gel from Pelage Pharmaceuticals that inhibits the mitochondrial pyruvate carrier; its registered Phase 2 trial (NCT06393452) tested it once daily in 78 adults with pattern hair loss, for safety and tolerability. It is not approved, not for sale, and has not been studied in alopecia areata or stress-related shedding.

learn Baicapil

Struggling with patchy hair loss like alopecia areata? Baicapil might help by reducing inflammation and reactivating growth. There is no published trial of Baicapil in alopecia areata. The anti-inflammatory and hair-density claims come from the ingredient's manufacturer and from laboratory work on its plant extracts, in people with androgenetic-type hair loss rather than autoimmune patchy hair loss.

learn procapil

Tried everything and still getting bald patches? Procapil may help calm the immune response Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.

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