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research Effects of Transcutol P and Precirol ATO-5 on Percutaneous Absorption of Flutamide from Emulgels

June 2021 in “Pharmaceutical sciences”

This study found that flutamide emulgels with 1% Transcutol P enhanced percutaneous absorption through rat skin more effectively than other formulations tested.

research Oral Contraceptives as Anti-Androgenic Treatment of Acne

16 citations , July 2002 in “JOGC/Journal of obstetrics and gynaecology Canada”

This review discusses treatments for female acne, highlighting the effectiveness of low-dose oral contraceptives and noting their similar side effects to placebo; it reports no new clinical results.

Steroid Plant Hormones: Effects Outside the Plant Kingdom

research Steroid plant hormones: Effects outside plant kingdom

46 citations , September 2014 in “Steroids”

This review suggests that brassinosteroids may have similar biological activities in both plants and other organisms, prompting further exploration of steroid regulation mechanisms across different life forms.

research Biopharmaceutical research on the choice of a non-steroidal anti-inflammatory agent in the development of combination gel for mastopathy therapy

September 2020 in “Zenodo (CERN European Organization for Nuclear Research)”

In this study, researchers identified indometacin as a suitable active ingredient for a combination gel aimed at treating mastopathy and preventing breast cancer, establishing its concentration using literary analysis, marketing research, and in vitro biopharmaceutical methods.

research Alopecia - the search for novel agents continues

11 citations , August 1997 in “Expert Opinion on Therapeutic Patents”

This review discusses nearly 70 patent applications for the treatment of androgenetic alopecia and other hair conditions, highlighting the mechanisms of action explored but reports no clinical results.

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community Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected.

494 upvotes 10 months ago

Finasteride users may have an increased risk of depression, anxiety, and suicidal thoughts, though some attribute these issues to hair loss itself. The link between finasteride and mental health effects is debated, with varying user experiences.

community Androsterone as a Neurosteroid Replacement Strategy for 5α-Reductase Inhibitor–Associated Sexual and Affective Dysfunction

in Research/Science 36 upvotes 2 months ago

Androsterone may help with sexual and affective dysfunction from finasteride by replacing disrupted neurosteroids without increasing androgenic side effects. Controlled testing is needed to confirm its effectiveness and safety.

community Is this real chat? Finasteride -> fountain of youth and longevity drug?

559 upvotes 1 year ago

Finasteride is discussed as a hair loss treatment with benefits like reduced prostate enlargement and skin aging, but it is not seen as a "fountain of youth." Users report mixed experiences, including side effects like decreased libido and dry eyes.

community Hair loss research is a money grab

227 upvotes 10 months ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community Trying to understand finasteride side effects and post finasteride syndrome

70 upvotes 5 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

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