January 2000 in “Linchuang pifuke zazhi” This case report describes a 58-year-old man with pretibial myxedema and hyperthyroidism, highlighting his cardiac symptoms, exophthalmos, weight loss, and specific dermatological findings over the last four years.
2 citations
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April 2022 in “International Journal of Research in Dermatology” In this study, pigmentary changes were the most common skin changes observed in pregnant women, affecting over 90% of the participants.
96 citations
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January 1997 in “Clinics in Dermatology” This study found that G protein-coupled estrogen receptor enhances melanin synthesis in melanoma cells through cAMP-PKA-MITF-TYR signaling, suggesting its potential as a drug target for chloasma treatment.
October 2024 in “Journal of the Endocrine Society” This case report highlights that in severe illnesses like sepsis, myxedema coma can occur with less elevated TSH levels than typical for primary hypothyroidism, likely due to inflammatory cytokines affecting TSH secretion, even when central lesions are absent.
12 citations
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April 1998 in “The Journal of Dermatology” This report describes a case of pretibial myxedema in an 18-year-old Japanese woman with Graves' disease, along with a review of 112 similar cases from the Japanese literature.