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research Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair

160 citations , July 2008 in “Experimental dermatology”

This review discusses the protective effects and mechanisms of melatonin in skin and suggests potential therapeutic applications in cutaneous medicine, reporting no new clinical findings.

research Hydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanism

52 citations , May 2011 in “APOPTOSIS”

In this study, cisplatin was found to induce cell death in human hair follicle cells through hydroxyl radical generation and Bcl-2 down-regulation, suggesting potential strategies for preventing chemotherapy-induced alopecia.

Preferential Recognition of Hydroxyl Radical-Modified Superoxide Dismutase by Circulating Autoantibodies in Patients with Alopecia Areata

research Preferential Recognition of Hydroxyl Radical-Modified Superoxide Dismutase by Circulating Autoantibodies in Patients with Alopecia Areata

12 citations , January 2014 in “Annals of Dermatology”

This study found an association between hydroxyl radical-modified SOD and alopecia areata, suggesting these modifications may lead to antibody induction in the condition.

research Protective Effects of Zizyphus jujuba and Fermented Zizyphus jujuba from Free Radicals and Hair Loss

9 citations , August 2014 in “Journal of The Korean Society of Food Science and Nutrition”

This study found that Zizyphus jujuba, especially when fermented with Saccharomyces cerevisiae, showed strong antioxidative activity and effectively promoted hair regrowth and prevented hair loss in a mouse model.

A Fast and Simple FIA-Chemiluminescence Method for the Evaluation of Roselle Flowers as Scavengers of Free Radicals Generated by UV-Irradiated Antibiotics

research A fast and simple FIA-chemiluminescence method for the evaluation of Roselle flowers as scavenger of the free radicals generated by UV irradiated antibiotics

4 citations , November 2018 in “Journal of Pharmaceutical and Biomedical Analysis”

This study found that a hydro-alcoholic extract of Roselle petals may reduce free radical production during UV-induced photodecomposition of antibiotics, potentially offering protective benefits for patients using similar topical antibiotics.

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Community Join

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community A tried and tested radical treatment for Hairloss in Men if you have enough self control.

6 months ago

The conversation suggests that abstaining from ejaculation for a few months may help stop or reverse hair loss by potentially increasing testosterone and reducing DHT levels. It also mentions the use of minoxidil and finasteride as effective treatments for maintaining hair after a hair transplant.

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Learn

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learn RU58841

RU58841: Is it safe or does it have strange side effects? (Because no one wants unpleasant surprises) There is no published human safety study of RU58841: the evidence is animal and tissue work only, human absorption has never been measured, and the side effects users describe are self-reported with unverified product.

learn Centella

Got small bald circles with no warning? Centella creams might calm the area and kickstart new growth. There is no published human trial of Centella asiatica for alopecia areata or any other hair loss; the only hair-related studies are cell-culture work. Community users describe Centella creams as soothing for an irritated scalp, not as regrowth treatments, and a new bald patch needs a doctor's diagnosis first.

learn Vitamin B5

Can a vitamin B5-rich hair mask rescue your strands when no shampoo seems to work? A vitamin B5-rich hair mask can improve hair health but won't replace shampoo.

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