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research Sanguisorba Officinalis Root Extract Has FGF-5 Inhibitory Activity and Reduces Hair Loss by Causing Prolongation of the Anagen Period

3 citations , January 2007 in “Nishinihon hifuka/Nishi Nihon hifuka”

This study found that Sanguisorba Officinalis Root Extract showed potential in reducing hair loss by inhibiting FGF-5 activity, extending hair growth phases in mice and reducing hair loss in human trials.

research RETORNOS PERIÓDICOS EM PORTADORES DE PRÓTESES PARCIAIS FIXAS EM DENTES NATURAIS E IMPLANTES ÓSSEO INTEGRADOS

January 2023 in “Brazilian Journals Editora eBooks”

research A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock

92 citations , September 2013 in “Journal of Investigative Dermatology”

This study found that peripheral clock genes, particularly BMAL1 and Period1, modulate human hair follicle cycling, suggesting their potential as therapeutic targets for affecting hair growth.

research Critical Developmental Periods for Effects on Male Rat Genitalia Induced by Finasteride, a 5α-Reductase Inhibitor

86 citations , March 1993 in “Toxicology and Applied Pharmacology”

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

research The changes in the hair cycle during gestation and the post-partum period

34 citations , May 2013 in “Journal of the European Academy of Dermatology and Venereology”

In this study, changes in hair cycle phases during pregnancy and the post-partum period showed a rise in telogen rates after delivery, especially among non-breastfeeding women, but no drastic exaggerations were noted.

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Community Join

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community Does periodic shedding make long hair with finasteride impossible?

in Finasteride/Dutasteride 7 upvotes 5 months ago

Finasteride can help extend the hair growth cycle and improve hair density, allowing for long hair despite initial shedding. Periodic shedding may occur, but it typically does not affect healthy hair significantly.

community Period(s) of shedding(s) is needed for Dutasteride/Minoxidil to work

in Progress Pictures 89 upvotes 1 year ago

Dutasteride and Minoxidil can cause initial hair shedding, which is normal and part of the process. Consistency and patience are crucial, as visible improvements may take over three years.

community What's the longest period it took you guys to so see results from fin/min pill?

in Research/Science 14 upvotes 5 months ago

It can take 2-3 years to see significant results from finasteride and minoxidil, with initial shedding and stabilization occurring within the first year. Some users experience slowed hair loss without regrowth, while others see improvement after a longer period.

community Female diffuse hair loss on spiro with irregular periods (photos) + genetic hair loss

in Female 16 upvotes 2 years ago

A 34-year-old woman is experiencing diffuse hair loss and irregular periods, possibly due to long-term spironolactone use. She is considering minoxidil and finasteride for treatment and seeking medical advice for androgenic alopecia and hormonal imbalances.

community Long term fin users (3+ years): Do you still shed periodically?

in Finasteride/Dutasteride 26 upvotes 1 year ago

Long-term finasteride users often experience periodic hair shedding due to natural hair cycles, even after several years of use. Some consider switching to dutasteride, but concerns about side effects and the effectiveness of finasteride remain common.

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Learn

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learn Hair Transplant

How long does recovery take after a hair transplant? Recovery after a hair transplant typically takes 7 to 14 days for initial healing.
How long does a hair transplant procedure take? A hair transplant procedure typically takes 4 to 8 hours.
When can I return to work after a hair transplant? Clinics most often say desk work is possible within a few days to a week; physical jobs need longer.
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learn RU58841

RU58841: Is it safe or does it have strange side effects? (Because no one wants unpleasant surprises) There is no published human safety study of RU58841, and a small 2026 study found it reaches the blood after one scalp application (Okutan et al.). The side effects users describe are self-reported and involve unverified product.

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