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Nuclear Magnetic Resonance Spectroscopy

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Procyanidin B-3, Isolated from Barley and Identified as a Hair-Growth Stimulant, Has the Potential to Counteract Inhibitory Regulation by TGF-β1

research Procyanidin B-3, Isolated from Barley and Identified as a Hair-Growth Stimulant, Has the Potential to Counteract Inhibitory Regulation by TGF-β1

36 citations , December 2002 in “Experimental dermatology”

Barley extract, specifically procyanidin B-3, can promote hair growth and counteract growth inhibition.

PH Dependence of the Coiled-Coil Structure of Keratin Intermediate Filament in Human Hair by 13C NMR Spectroscopy and the Mechanism of Its Disruption

research PH Dependence of the Coiled-Coil Structure of Keratin Intermediate Filament in Human Hair by 13C NMR Spectroscopy and the Mechanism of Its Disruption

7 citations , February 1998 in “Polymer journal”

Keratin structure in hair is stable at pH 5-6 but disrupts between pH 6-7.

research Isolation and Structural Identification of a Novel Minoxidil Analogue in an Illegal Dietary Supplement: Triaminodil

1 citations , October 2017 in “Food Additives & Contaminants: Part A”

A new minoxidil-like substance, triaminodil, was found in an illegal hair growth supplement.

Synthesis of Analogues of Cercidin, an Antimicrobial Compound of Cercidiphyllum Japonicum: Glycosylation of Methyl Gallate with Ulosyl Bromides

research Synthesis of Analogues of Cercidin, an Antimicrobial Compound of Cercidiphyllum Japonicum: Glycosylation of Methyl Gallate with Ulosyl Bromides

June 2025 in “Natural Product Communications”

Researchers created 10 new compounds similar to cercidin, which could lead to new antibiotics.

research The Swelling Behavior of Hair Studied Through the Structural Change of Keratin Protein During the Permanent Waving Treatment

November 2024 in “Biophysical Chemistry”

Hair structure changes immediately during perm treatment, with initial damage partially restored later.

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community Waiting to start treatment until Kintor KX-826 Phase 2 data is published?

in Chat 17 upvotes 3 years ago

People are waiting for KX-826 (Pyrilutamide) Phase 2 data to decide on hair loss treatments, with some considering finasteride or minoxidil in the meantime. Pyrilutamide is seen as a potentially stronger and safer alternative to finasteride, but concerns about side effects and availability remain.

community Binding affinity of pyrilutamide!

in Update 170 upvotes 3 years ago

Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

community How to increase Pyri concentration from 0.5% to 1% wihout using more volume ( 2ml x 2 per say for example )

in Chat 6 upvotes 1 year ago

OP wants to increase pyrilutamide concentration from 0.5% to 1% while already using finasteride. Users suggest waiting for a commercial 1% solution and caution against using grey market products.

community The New, Improved CB-03-01/Setipiprant Group Buy

25 upvotes 9 years ago

The group buy for CB-03-01, a topical anti-androgen for hair loss, was postponed and refunded due to issues with the product's form and solubility. The product, also known as Breezula, is an alternative to finasteride with fewer side effects, but its official release is delayed until 2021.

community Pyrilutamide vs topical finasteride

in Finasteride/Dutasteride 2 upvotes 8 months ago

The user is considering switching to topical finasteride or pyrilutamide to stabilize hair loss before a hair transplant, currently using oral minoxidil and finasteride. Suggestions include sticking to the current regimen as it is already potent, and caution against using pyrilutamide from unreliable sources.

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