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In this study, ethanol was found to enhance GABAergic neurosteroid production and inhibit long-term potentiation in rat hippocampal slices via unblocked NMDA receptor activation, effects reversible by specific inhibitors.

This study found that Asiasari radix extract may reduce hyperalgesia in mice by modulating NMDA and GABAA receptor activities without affecting cyclooxygenase activity.

In this pilot study, no significant differences were observed between memantine and placebo groups in young adults with Down syndrome on the primary memory outcomes, but some improvement was noted in a secondary measure.

This study reported that in rat retinas under high pressure, allopregnanolone synthesis increased and helped reduce pressure-induced damage through GABAA receptors, suggesting potential therapeutic use in glaucoma.

This study found that boosting the synthesis of neural-derived 17β-estradiol effectively counteracted the impairment of hippocampal long-term potentiation caused by amyloid beta 1-42 in rat hippocampal slices, with the effect seemingly linked to glutamate NMDAR signaling.