48 citations
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October 2010 in “Archives of Dermatological Research” In this study, Juvéderm repeat treatments maintained wrinkle correction in nasolabial folds for up to 21 months and required significantly less filler than the initial treatment, indicating potential benefits for patients.
13 citations
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January 2017 in “Plastic and reconstructive surgery. Global open” This study found that Juvéderm Ultra Plus was safe and effective for correcting severe nasolabial folds in a Chinese population, requiring less volume than Restylane while achieving similar responder rates, with fewer severe treatment site reactions.
12 citations
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October 2022 in “Facial Plastic Surgery” This study found that polycaprolactone gel injections were significantly more effective than sodium hyaluronate gel in improving nasolabial fold severity for Chinese patients over 12 months, with similar rates of mild injection-related adverse events between the groups.