research 058 The pattern of Fas and Fas ligand expression in alopecia areata
The Fas/FasL pathway may play a role in alopecia areata.
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5 / 545 resultsresearch Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition
This study found that JAK inhibitors promote hair regrowth in both mice and human alopecia areata cases by blocking key immune pathways involved in disease development.
research Treatment of alopecia areata: “What is new on the horizon?”
This review discusses potential new drug treatment strategies for alopecia areata based on genome-wide association study findings, but it reports no new clinical results.
research Genome-wide association study in alopecia areata implicates both innate and adaptive immunity
This study identified key genetic regions associated with alopecia areata, highlighting both acquired and innate immune involvement, with a novel link to the upregulation of ULBP ligands in autoimmune disease.
research An immune regulatory CCT repeat containing oligodeoxynucleotide capable of causing hair loss in male mice
This study reported that CCT oligodeoxynucleotide induced patchy hair loss in male mice with specific genetic traits, suggesting gender and genetic preferences in immune response.
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