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research 1115 Interrogating the gut-skin axis for acne and sebaceous gland health – a case study of nicotinic acid
This study found that while nicotinic acid significantly inhibited human sebaceous organoid growth in vitro, the predicted skin concentrations from gut microbiome-derived levels were far below the effective dose, suggesting high oral doses would be necessary for therapeutic effects.
research 1317 Nicotinic acid suppresses sebaceous lipid synthesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA2)
The researchers reported that nicotinic acid normalized excessive sebaceous lipogenesis without affecting basal lipogenesis and suggested potential anti-acne benefits.
research The Nutritional Approach to Experimental Dermatology. Nutritional Dermatoses in the Rat
This review discusses the historical understanding of nutritional dermatoses related to Vitamin B complex deficiencies and reports no new experimental results.
research Diabetex: A novel approach for diabetic wound healing
This study found that Diabetex significantly improved wound healing and reduced fasting blood sugar in diabetic rats, showing potential as a safe and economic treatment strategy for diabetic-resistant wounds.
research Cutaneous Syndromes Produced as Side Effects of Triparanol Therapy
This article reviews historical reports of skin changes, such as pseudoacanthosis nigricans, associated with cholesterol-lowering drugs like triparanol and nicotinic acid, but presents no new clinical findings.
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5 / 98 resultscommunity 10months on minoxidil as an “ok responder”
The user added topical minoxidil to their finasteride regimen, resulting in healthier hair and some regrowth, especially after quitting nicotine. They experienced minimal shedding and noted improvements in hairline density, finding the treatment mostly preventative.
community The perfect reverse reverse hair-loss nuclear stack for those who feel left out
A satirical discussion on intentionally inducing hair loss using harmful habits and substances like cigarettes, junk food, anabolic steroids, and stress. The conversation humorously suggests extreme measures like chemotherapy and hydrofluoric acid, while also mentioning the ineffectiveness of sulfates and pumpkin seed oil in hair loss prevention.
community 4 months of progress, lots of new terminal hairs, diffuse thinning. 31m
A 31-year-old man shares his 4-month hair regrowth progress using topical minoxidil, topical finasteride, microneedling, biotin, and other supplements. He reports new hair growth despite experiencing side effects from finasteride and plans to continue his regimen for further improvement.
community One year off fin/min and I regret it
The user regrets stopping finasteride and minoxidil due to side effects but plans to resume treatment. They consider using finasteride every other day and continuing topical minoxidil to manage side effects while maintaining hair.
community Does anyone have a list of vitamins that could help alongside dut and min?
The conversation is about hair loss treatments, specifically using dutasteride and oral minoxidil, and exploring additional vitamins and supplements like vitamin D, zinc, biotin, and omega-3 to support hair health. Users suggest getting a blood panel to identify deficiencies and emphasize the importance of protein and overall nutrition.
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