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GlossaryLipocalin-2 (NGAL)

protein involved in immune response and iron regulation

Lipocalin-2 (LCN2), also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a protein involved in the body's immune response and iron metabolism. It helps to sequester iron, limiting bacterial growth during infections, and is also used as a biomarker for kidney injury and other inflammatory conditions.

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research Neutrophil Gelatinase-Associated Lipocalin Is a Marker for Dysregulated Keratinocyte Differentiation in Human Skin

96 citations , December 2002 in “Experimental dermatology”

NGAL indicates abnormal skin cell differentiation.

research Expression of Neutrophil Gelatinase-Associated Lipocalin in Calcium-Induced Keratinocyte Differentiation

20 citations , January 2008 in “Journal of Korean Medical Science”

NGAL may help maintain skin balance and is linked to skin disorders and cancers.

Acquired Acrodermatitis Enteropathica in a 28-Year-Old Male with Type 1 Diabetes

research Acquired Acrodermatitis Enteropathica in a 28-Year-Old Male with Type 1 Diabetes

2 citations , May 2021 in “Case reports in dermatological medicine”

A 28-year-old man with type 1 diabetes had skin and hair issues due to zinc deficiency.

Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity

research Apoptosis May Explain the Pharmacological Mode of Action and Adverse Effects of Isotretinoin, Including Teratogenicity

66 citations , January 2017 in “Acta dermato-venereologica”

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Paraneoplastic Alopecia Associated With Internal Malignancies in Cats

research Paraneoplastic Alopecia Associated With Internal Malignancies in Cats

48 citations , March 1997 in “Veterinary Dermatology”

Some cats with sudden hair loss and tiredness might have cancer-related alopecia.

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