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research Author response: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes

September 2020

This study observed that nevus melanocytes do not exhibit signs of senescence, suggesting that their growth arrest is due to cell interactions and not directly caused by BRAF activation.

research Decision letter: Dynamics of nevus development implicate cell cooperation in the growth arrest of transformed melanocytes

August 2020

This study suggests that the growth arrest of nevus melanocytes is not due to oncogene-induced senescence but rather to collective cell interactions, similar to those in normal tissue size regulation.

research Nevus comedonicus syndrome: a case associated with multiple basal cell carcinomas and a rudimentary toe

38 citations , June 2005 in “International Journal of Dermatology”

This case report describes a 28-year-old man with widespread pigmented basal cell carcinomas and recurrent infections that were challenging to control, associated with nevus comedonicus and a rudimentary toe.

research LB1031 Immune Cell-Mediated Amplification of Stem Cell Activation in Hairy Melanocytic Nevus via Osteopontin-CD44 Axis

1 citations , July 2024 in “Journal of Investigative Dermatology”

Immune cells boost stem cell activity in hairy moles, causing more hair growth.

research Novel mutation in PTCH1 gene in a patient with basal cell nevus syndrome and uterus bicornis

August 2019 in “Anais Brasileiros de Dermatologia”

This article reviews the case of a patient diagnosed with basal cell nevus syndrome and reports no new research findings.

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community Summary of future treatments from 2020

51 upvotes 1 year ago

Hair loss treatments include finasteride, minoxidil, microneedling, dutasteride, CB-03-01, RU-58841, and experimental options like KY-19382 and stem cell therapy. Some treatments are considered ineffective or risky, such as ketoconazole, PRP, and low-level laser therapy.

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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