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research Multisystem Adverse Effects of Isotretinoin: Mechanistic Insights and Clinical Implications

January 2026 in “International Journal of Innovative Technologies in Social Science”

Isotretinoin effectively treats severe acne but can cause various side effects, with the most serious being birth defects, requiring careful monitoring and contraception.

research Neuropsychiatric Adverse Events of Montelukast: An Analysis of Real-World Datasets and Drug-Gene Interaction Network

December 2021 in “OPAL (Open@LaTrobe) (La Trobe University)”

Montelukast is linked to increased risks of suicidal thoughts and depression.

research Finasteride-Induced Neuropsychiatric Reactions

December 2025 in “The Journal of Clinical Psychiatry”

Finasteride can cause depression and suicidal thoughts; safer alternatives are recommended.

research Repurposing Steroidogenesis Inhibitors for the Therapy of Neuropsychiatric Disorders: Promises and Caveats

10 citations , May 2018 in “Neuropharmacology”

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

research Adverse Effects of Voriconazole: Over a Decade of Use

100 citations , September 2016 in “Clinical transplantation/Clinical transplantation.”

Voriconazole can cause serious side effects, especially in long-term use.

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community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 1 year ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

community Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected.

in Research/Science 493 upvotes 5 months ago

Finasteride users may have an increased risk of depression, anxiety, and suicidal thoughts, though some attribute these issues to hair loss itself. The link between finasteride and mental health effects is debated, with varying user experiences.

community 4 months on finasteride + minoxidil

in Progress Pictures 293 upvotes 5 months ago

The user experienced significant hair improvement after four months using oral finasteride, topical minoxidil, and a daily caffeine shampoo, with no side effects. The discussion includes varying opinions on the effectiveness and side effects of finasteride.

community Do you believe these studies are real or just fear mongering

in Finasteride/Dutasteride 157 upvotes 5 months ago

Finasteride can regrow hair but may cause depression and suicidal thoughts in some users. The connection between finasteride and mental health issues is debated, with some attributing it to pre-existing conditions or stress.