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research Saliva Secretion in Engrafted Mouse Bioengineered Salivary Glands Using Taste Stimulation

10 citations, January 2014 in “Journal of prosthodontic research”

Bioengineered salivary glands in mice can produce saliva when tasting sour or bitter, but have different protein levels and nerve signals compared to natural glands.

research Segmental Vitiligo: Characteristics, Treatment, and Prognosis

2 citations, January 2019 in “Springer eBooks”

Segmental Vitiligo is a stable, early-onset form of vitiligo that responds well to early treatment and is ideal for repigmentation studies.

research Hair Growth Modulation by Adrenergic Drugs

22 citations, August 1999 in “Experimental Dermatology”

Certain drugs can cause early hair growth in mice by affecting the nerves.

research Neurobiology, Stem Cell Biology, and Immunology: An Emerging Triad for Understanding Tissue Homeostasis and Repair

1 citations, October 2022 in “Annual review of cell and developmental biology”

The nervous system helps control stem cell behavior and immune responses, affecting tissue repair and maintenance.

research Hair Follicle Stem Cells as a Skin-Organizing Signaling Center During Adult Homeostasis

25 citations, April 2021 in “The EMBO Journal”

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

View more "neuropeptide y-positive sympathetic nerves" in research →

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community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 71 upvotes 4 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community He used Dutasteride for 20 years. Interview

in Treatment 106 upvotes 4 days ago

community C’est terrible - at my wits end

in Female 443 upvotes 1 year ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 127 upvotes 4 months ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.