September 2026 in “International Journal of Dermatology” This review discusses the clinical presentation, diagnosis, and treatment of scalp dysesthesia, highlighting a potential neuropathic component and the inconsistent efficacy of various management strategies without reporting new clinical results.
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October 2025 in “Cureus” In this case report, a 30-year-old male with alopecia universalis and autoimmune conditions experienced treatment failure with JAK inhibitors, including ritlecitinib, and developed severe musculoskeletal pain, indicating a potential novel adverse effect that warrants further pharmacovigilance.
September 2025 in “Cureus” In this case report, the researchers documented a rare instance of plica neuropathica, characterized by matted and twisted hair, occurring alongside diffuse alopecia, marking the first such documented association and emphasizing its diagnostic challenges in identifying causes of alopecia.
April 2024 in “International journal of research in dermatology” In this report, researchers document a rare case of a 16-year-old female on azathioprine presenting with both anagen effluvium and plica neuropathica, highlighting a unique instance of overlapping hair conditions potentially linked to medication use.
December 2023 in “Frontiers in pharmacology” In this study, intrathecal progesterone administration initially worsened mechanical allodynia in mice after nerve injury, but later reduced pain when applied during the maintenance phase, highlighting distinct roles for cytochrome P450c17 and 5α-reductase in neuropathic pain modulation.