74 citations
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July 1991 in “The Journal of Urology” Minoxidil works better than nitroglycerin for treating impotence with fewer side effects.
28 citations
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May 1994 in “The Journal of Urology” Topical minoxidil not effective for erectile dysfunction treatment.
25 citations
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December 2001 in “Expert Opinion on Pharmacotherapy” Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.
2 citations
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January 1998 in “Neurourology and Urodynamics” This case study reported on a patient with adrenomyeloneuropathy (AMN) who developed neurogenic bladder dysfunction, characterized by urinary urgency, difficulty voiding, and other neurological symptoms. The patient began losing hair at age 12 and experienced progressive symptoms, including erectile impotence and gait disturbance, by age 25. By age 31, he exhibited spastic paraparesis and disturbed vibratory sensation, with diagnostic tests confirming AMN through low serum cortisol response and increased very long chain fatty acids. Urodynamic studies revealed impaired bladder function, with residual urine volumes increasing from 50 ml to 200 ml over time, alongside decreased bladder capacity and marked detrusor hyperreflexia. The study suggested that demyelinating lesions in the peripheral nerves and central nervous system contributed to the micturitional disturbances observed in this patient.
19 citations
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October 2018 in “PLOS ONE” 5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.