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This review reports that alopecia, particularly alopecia areata, significantly impacts mental health and quality of life through stress and immune mechanisms, with treatments like Janus kinase inhibitors showing promise for improving both hair regrowth and psychological well-being.

This review found significant psychosocial impacts of alopecia, noting that those with alopecia, particularly alopecia areata, experience higher rates of depression and anxiety. The review also highlighted new treatments like Janus kinase inhibitors that improve both hair regrowth and quality of life.

This study concluded that both finasteride and dutasteride therapies significantly increased chromogranin A serum levels in men with benign prostatic hyperplasia, suggesting an activation of neuroendocrine differentiation.

This study found that human scalp hair follicles can respond to corticotropin releasing hormone stimulation similarly to the classical HPA axis, including up-regulating cortisol production and activating neuroendocrine feedback loops.

This review discusses sex differences in the neuroendocrine response to stress, focusing primarily on rodent studies, and highlights open questions about the roles of gonadal hormones and sex chromosomes.