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research Developmental Mapping of Hair Follicles in the Embryonic Stages of Cashmere Goats Using Proteomic and Metabolomic Construction

September 2023 in “Animals”

Hair follicle development in cashmere goats involves dynamic changes in proteins and metabolites, with key roles for oxytocin, MAPK, and Ca2+ pathways.

Transcriptome Sequencing Reveals the Expression Profiles of lncRNAs and mRNAs in Goat Skin Tissues With Different Types of Wool Coats

research Transcriptome Sequencing Reveals the Expression Profiles of lncRNAs and mRNAs in Goat Skin Tissues With Different Types of Wool Coats

1 citations , May 2025 in “Scientific Reports”

The study identified key genes and pathways that influence goat wool quality and growth.

Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus

research Transcriptome Dynamics Reveal Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Cashmere Growth Cycle in Capra Hircus

October 2021 in “Research Square (Research Square)”

Melatonin affects certain genes and pathways involved in cashmere goat hair growth.

research Integration Analysis of Transcriptome and Proteome Reveals the Mechanisms of Goat Wool Bending

6 citations , April 2022 in “Frontiers in cell and developmental biology”

The research identified key proteins and genes that may influence wool bending in goats.

research Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats

127 citations , March 2016 in “PLoS ONE”

Key genes and pathways crucial for hair follicle development in cashmere goats were identified, aiding fleece production improvement.

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community Finasteride does deplete important nuero-active steroids

in Research/Science 9 upvotes 2 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

community 5 alpha reductase type 1 is in brain tissue producing the main endogenous gabaergic allopregnanolone, not 2. How can finasteride as a 5ar2 lower that?

in Finasteride/Dutasteride 27 upvotes 1 year ago

Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.

community risks with finasteride and dutasteride

in Research/Science 142 upvotes 7 months ago

Finasteride and dutasteride have potential risks, including post-finasteride syndrome, but are commonly used for hair loss. RU58841, minoxidil, and needling are suggested as alternatives, though all treatments carry risks.

community The safest way to use finasteride - my research

in Finasteride 24 upvotes 8 years ago

The post discusses microdosing finasteride to minimize side effects while treating hair loss. The user also mentions using minoxidil, biotin, and ketoconazole.

community 22M started fin/min/dermaroller again after stopping for almost 2 years (2months progress)

in Progress Pictures 35 upvotes 4 months ago

A 22-year-old resumed using finasteride, minoxidil, and a 0.5mm dermaroller after stopping for two years, experiencing positive results and improved mood. The discussion includes debates on the effects of finasteride on neurosteroids and the optimal dermaroller needle length for hair regrowth.

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