7 citations
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January 2016 in “Methods in molecular biology” This report introduces a tissue-engineered nerve conduit combining hfNCSCs-derived neurons and acellular nerve grafts to potentially repair long-distance peripheral nerve injuries.
155 citations
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August 1991 in “Journal of The American Academy of Dermatology” This article reviews methotrexate's pharmacokinetics and toxicity, emphasizing the role of urinary excretion and leucovorin in avoiding most toxic reactions; it provides no new clinical results.
January 2018 in “Investigative Ophthalmology & Visual Science” This study observed retinal and optic nerve damage in patients who had taken finasteride, suggesting potential ocular toxicity associated with the drug's use.
4 citations
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July 2024 in “Pharmacology Research & Perspectives” In this phase 2a study of adults with alopecia areata, researchers observed that ritlecitinib treatment did not result in significant differences in brainstem auditory evoked potential changes or axonal swelling compared to placebo, suggesting the dog toxicity findings may not be clinically relevant in humans.
3 citations
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October 2001 in “British Journal of Ophthalmology” In this case, intralesional cidofovir showed a successful outcome for treating SCC without systemic toxicity, suggesting it may be worth considering alongside surgical excision.