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Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2

research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2

6 citations , September 2023 in “Experimental physiology”

In this study, researchers identified the PLD-mGluR protein in primary mechanosensory terminals as the homomeric GluK2 kainate receptor, functioning purely metabotropically, which is suggested to be common to various sensory endings.

research Characteristic intraepidermal nerve fibre endings of the intervibrissal fur in the mystacial pad of the rat: morphological details revealed by intravital methylene blue staining and the zinc iodide-osmium tetroxide technique

5 citations , July 1999 in “Journal of Anatomy”

This study found that methylene blue staining may reveal anatomical details of intraepidermal nerve fibre endings in the rat mystacial pad with greater clarity than the zinc iodide-osmium tetroxide technique.

research Characteristic intraepidermal nerve fibre endings of the intervibrissal fur in the mystacial pad of the rat: morphological details revealed by intravital methylene blue staining and the zinc iodide‐osmium tetroxide technique

5 citations , July 1999 in “Journal of Anatomy”

This study observed that methylene blue staining and zinc iodide-osmium tetroxide techniques effectively revealed anatomical details of intraepidermal nerve fibre endings in the rat's mystacial pad, suggesting their potential role in mechanoreception.

research Fine Structure of Perifollicular Nerve Endings in Human Hair

15 citations , December 1972 in “Journal of Investigative Dermatology”

research Effects of ultraviolet radiation on human cutaneous nerve fibres

9 citations , June 2009 in “Cell Proliferation”

This study found that Cream 1 effectively prevented UV radiation-induced nerve ending damage in human skin samples, unlike placebo and SPF15 creams.

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community Pelage Pharmaceuticals’ PP405 and its Impact on Follicular Regeneration to be Presented at the American Academy of Dermatology (AAD) Annual Meeting 2026

122 upvotes 6 months ago

PP405 shows promise in regenerating hair by activating dormant follicles. Other treatments like VDPHL01 and Breezula are also advancing, providing new hope for hair loss solutions.

community Minoxidil Eye Bags and Dark Circles

24 upvotes 3 years ago

Minoxidil users report dark circles and eye bags. Solutions include water pills, caffeine serum, retinol, and collagen peptides.

community GH peptides + KLOW blend saved my hair. before and after pics.

833 upvotes 6 months ago

Using finasteride and peptides, including GHK-Cu, improved hair thickness and regrowth. The user also used a KLOW blend and CJC/IPA for better sleep and recovery.

community Japan-led "Third Cell" Discovery: Is this the missing link for full follicle regeneration?

in Technology 132 upvotes 6 months ago

A new "third cell" discovery in Japan could be key to fully regenerating hair follicles, with human trials possibly starting in 2027-2028. AI is expected to accelerate medical discoveries, potentially leading to a hair loss cure within a few years.

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