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      Macrophages as Central Mediators of Sympathetic Neuro-Immune Interplay in Autoimmunity

      research Macrophages as central mediators of sympathetic neuro-immune interplay in autoimmunity

      December 2025 in “Frontiers in Immunology”
      This review highlights that disturbances in neuroimmune communication, particularly between sympathetic nerves and macrophages, may contribute to autoimmune diseases like rheumatoid arthritis and type 1 diabetes, and suggests potential therapeutic avenues by restoring this communication in preclinical and early clinical studies.
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      research Contents

      January 2009 in “Oral and Maxillofacial Surgery Clinics of North America”
      The document concludes that understanding risks, careful patient selection, precise surgery, quick complication management, and good communication can improve cosmetic facial surgery outcomes.

      research Nerve cells and nervous systems: an introduction to neuroscience

      34 citations , November 1991 in “Choice Reviews Online”
      This work reviews the structure and functions of the nervous system, covering topics from nerve cell properties to the mechanisms of learning and memory, but does not present new research findings.

      research PIK3CA gain-of-function mutation in Schwann cells leads to severe neuropathy and aerobic glycolysis through a non-cell autonomous effect

      June 2025 in “Proceedings of the National Academy of Sciences”
      In this study, a mouse model with a PIK3CA gain-of-function mutation in Schwann cells revealed unique communication with neighboring cells and a glycolytic shift in peripheral nerves, and early alpelisib treatment significantly improved symptoms, though efficacy declined with delayed administration due to limited drug penetration.

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