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T-Cell Induced-Self MHC Class I/Peptide Complexes May Enable De Novo Tolerance Induction to Neo-Antigens Occurring Outside of the Thymus

research T-Cell Induced-Self MHC Class I/Peptide Complexes May Enable De Novo Tolerance Induction to Neo-Antigens Occurring Outside of the Thymus

8 citations, October 2016 in “Experimental dermatology”

Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.

research Acquired Immunogenicity of DNA After Modification with Malondialdehyde in Patients with Alopecia Areata

10 citations, March 2014 in “Scandinavian journal of clinical and laboratory investigation”

Malondialdehyde-modified DNA may trigger an immune response in alopecia areata patients.

research Alopecia Areata: A Review of the Role of Oxidative Stress, Possible Biomarkers, and Potential Novel Therapeutic Approaches

15 citations, January 2023 in “Antioxidants”

Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.

research Cell Surface B2m-Free Human Leukocyte Antigen Monomers and Dimers: Are They Neo-HLA Class and Proto-HLA?

3 citations, July 2023 in “Biomolecules”

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

research Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair

24 citations, May 2016 in “Stem Cell Reviews and Reports”

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

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Community Join

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community Is it time for my 3-Year Old Nephew to get on Fin & Min? 😓

in Satire 517 upvotes 2 years ago

Hair loss in a 3-year-old, with various treatments discussed such as minoxidil, finasteride, dutasteride, RU58841 and biotin supplementation. Some people suggested shaving the head and growing a beard or getting a partial hairpiece instead of attempting to treat it.

community To anyone starting their hair loss battles. [Sorry for long post]

6 upvotes 10 years ago

The user recommends using Regenepure (keto shampoo), Lipogaine (minoxidil), and NatureMade Biotin pills for hair loss treatment and advises against taking finasteride (propecia) without considering potential side effects. They share their own experience with these treatments and suggest reading about both the benefits and risks before deciding on finasteride.

community If you can give one advice to your younger self then what that would be?

in Research/Science 2725 upvotes 5 months ago

Users discussed hair loss treatments, specifically minoxidil and finasteride. They shared personal experiences and advice on starting these treatments early.

community I was hesitant, but I pulled it. Thoughts?

in Shaved/buzzed 2707 upvotes 5 months ago

A user shared their experience with hair loss, showing a shaved/buzzed look. Replies praised their appearance and discussed treatments like minoxidil, finasteride, dutasteride, and oral minoxidil.

community Hair Transplant Results after 6 months . 3500 grafts. NW 6

in Progress Pictures 373 upvotes 10 months ago

The user underwent a hair transplant with 3500 grafts and has been using Finasteride and Minoxidil for 5.5 months, seeing some growth. They plan to have a second transplant for the crown area and are seeking opinions on future results and density improvement.

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