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In this paper, regression of proliferative necrotizing otitis externa lesions in young cats was reported following systemic and topical immunomodulatory therapy.

In this study, proliferative and necrotizing feline otitis externa in four domestic shorthair cats improved with topical 0.1% tacrolimus treatment, despite previous ineffective therapies.

In this review, the authors discussed the clinical presentations and management of feline immune-mediated skin diseases such as erythema multiforme and Stevens-Johnson syndrome, noting that although these conditions are rare, they can severely affect cats' quality of life.

The study reported that topical 0.1% tacrolimus improved proliferative and necrotizing otitis externa in cats, with complete lesion resolution in some cases.

Diabetes can cause a variety of skin disorders, some of which may signal more serious health issues.