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research New developments in our understanding of acne pathogenesis and treatment

466 citations , June 2009 in “Experimental dermatology”

This review discusses recent advances in understanding acne pathobiology, highlighting the potential for developing new customized therapies, but it reports no new clinical findings.

research Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons

419 citations , March 2005 in “Proceedings of the National Academy of Sciences”

This study demonstrated that ND-GFP stem cells from the hair-follicle bulge area can differentiate into various cell types, including neurons, suggesting their potential as a source for therapeutic applications.

research Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells

396 citations , May 2011 in “Cell stem cell”

This study found that Shh from neurons signals to Gli1-expressing cells in the hair follicle, cultivating a niche where these bulge cells can potentially transform into epidermal stem cells in wound healing.

research The Neurobiology of Sexual Function

393 citations , November 2000 in “Archives of General Psychiatry”

This review discusses the neurobiology of sexual function and reports no new results; the authors cover multiple endocrine and neurotransmitter influences on sexual desire, arousal, and orgasm stages.

research New aspects of vitamin D metabolism and action — addressing the skin as source and target

378 citations , February 2020 in “Nature Reviews Endocrinology”

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Community Join

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community Need some advice on Hair Transplant

4 upvotes 2 days ago

The conversation is about planning a hair transplant in Turkey, with advice on choosing clinics and doctors, focusing on factors like doctor involvement, clinic reputation, and realistic graft limits per session. Users recommend not exceeding 4000 grafts per session to avoid donor area damage and suggest considering two separate procedures for better graft survival.

community Nearing 1 Year--Progress Pics and Routine Changes

185 upvotes 1 week ago

The user experienced gradual hair loss and began using finasteride and later minoxidil to improve hair thickness, achieving significant progress. They adjusted their finasteride dosage to 1mg on Monday, Wednesday, and Friday, and take 2.5mg of minoxidil daily, reporting satisfaction with the results.

community Need help evaluating my hairloss and recovery progress

4 upvotes 1 week ago

A user is seeking advice on their hair loss treatment progress, using dutasteride, minoxidil, and ketoconazole shampoo. They express disappointment with their progress and seek opinions on their hairline improvement.

community New human study (Aug 2026) directly tested whether RU58841 stays local - it doesn't

8 upvotes 1 week ago

RU58841 is absorbed systemically in humans, contradicting claims it stays local, but no harm is proven. Alternatives like CB-03-01 or KX-826, especially with finasteride, are suggested for safety.

community NEW PHOTOS- 10 MONTHS MARK - NW7 Diffuse going for the comeback. (49M)

216 upvotes 3 weeks ago

A 49-year-old man shared his 10-month hair recovery progress using finasteride 1.25mg and topical minoxidil 5%, noting significant improvement after initial worsening and emphasizing patience. He also mentioned weight loss and plans to continue the regimen until further evaluation.

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