This study found that vinblastine's metabolites show binding affinities for receptors linked to nausea and alopecia, suggesting potential changes to its structure could minimize these side effects during chemotherapy.
82 citations
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May 2006 in “Cancer Nursing” This study found that symptom monitoring by parents of children undergoing chemotherapy identified nausea as the most common issue, with fatigue, eating problems, and fever also frequently observed.
53 citations
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August 2014 in “Cochrane library” This review found no evidence supporting the efficacy of methotrexate for inducing remission in active ulcerative colitis compared to placebo or active comparators.
51 citations
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August 2015 in “Cochrane library” This systematic review reports that there is currently no evidence supporting methotrexate for maintaining remission in ulcerative colitis; further large-scale trials are needed to assess its efficacy and safety.
45 citations
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November 1979 in “British Journal of Dermatology” This report describes a case of hypertrichosis associated with minoxidil use and suggests that nearly all patients on this drug may experience this side effect.