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research Sirtuins pathways and redox homeostasis: a pilot study on young and old monozygotic twins

August 2015 in “Free Radical Biology and Medicine”

This study explores the correlation between sirtuins' expression, histone deacetylation, and redox status in young and old monozygotic twins to understand their role in age-related mechanisms.

research PBX1-SIRT1 Positive Feedback Loop Attenuates ROS-Mediated HF-MSC Senescence and Apoptosis

12 citations , August 2022 in “Stem cell reviews and reports”

This study found that PBX1 overexpression reduces hair follicle-derived mesenchymal stem cell senescence and apoptosis by interacting with SIRT1 and PARP1, highlighting a potential mechanism for addressing aging-related diseases.

research Epigenetic control of adult stem cell function

179 citations , July 2016 in “Nature Reviews Molecular Cell Biology”

This review examines how epigenetic dysregulation affects adult stem cell function, noting that impacts range from minor to serious disruptions in tissue homeostasis and potential cancer development.

research PBX1-SIRT1 positive feedback loop attenuates ROS-mediated HF- MSC senescence and apoptosis

3 citations , April 2022 in “Research Square (Research Square)”

In this study, the researchers identified a PBX1-SIRT1-PARP1 axis that plays a crucial role in reducing senescence and apoptosis in hair follicle-derived mesenchymal stem cells.

research Pre-receptor regulation of the androgen receptor

56 citations , November 2007 in “Molecular and cellular endocrinology”

This study identified enzymes responsible for regulating androgen action in the human prostate, suggesting that inhibiting AKR1C2 or RL-HSD may have therapeutic potential in androgen insufficiency or benign prostatic hyperplasia, respectively.

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community Going to inject NAD+ and GHL-Cu into Scalp for a few months

in Chat 1 upvotes 1 year ago

The conversation discusses a user's plan to inject NAD+ and GHK-Cu into their scalp to improve hair health, with concerns raised about the risks of infection and necrosis. Alternatives like finasteride, dutasteride, microneedling, oral minoxidil, and scalp massages are suggested.

community 5 months no fin or min just copper peptides and nad+

4 upvotes 7 months ago

The conversation discusses hair regrowth progress using copper peptides and NAD+ without finasteride or minoxidil. Users suggest comparing wet and dry hair photos for better assessment.

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