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GlossaryMyxedema

severe hypothyroidism causing skin and tissue swelling

Myxedema is a severe form of hypothyroidism, where the thyroid gland does not produce enough thyroid hormones. This condition can lead to symptoms such as extreme fatigue, weight gain, cold intolerance, and swelling of the skin and tissues, particularly noticeable in the face and lower legs. In extreme cases, it can progress to myxedema coma, a life-threatening emergency requiring immediate medical attention.

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research Thyroid Hormone Action on Skin

24 citations , July 2011 in “PubMed”

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

research A Case of Atypical Myxedema in Hypothyroidism

April 2019 in “Journal of the Endocrine Society”

A woman with severe hypothyroidism had a rare skin condition usually linked to a different thyroid disease.

research Dermatologic Manifestations of Endocrine Disorders

11 citations , July 2012 in “Current Opinion in Pediatrics”

Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.

research Thyroid Hormone Action on Skin

44 citations , July 2011 in “Dermato-endocrinology”

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

research Pathologies of the Skin and Its Appendages in Endocrine Diseases

January 2016 in “Dermatology Review”

Endocrine disorders can cause various skin and hair issues.

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