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GlossaryMyxedema

severe hypothyroidism causing skin and tissue swelling

Myxedema is a severe form of hypothyroidism, where the thyroid gland does not produce enough thyroid hormones. This condition can lead to symptoms such as extreme fatigue, weight gain, cold intolerance, and swelling of the skin and tissues, particularly noticeable in the face and lower legs. In extreme cases, it can progress to myxedema coma, a life-threatening emergency requiring immediate medical attention.

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research A Case of Atypical Myxedema in Hypothyroidism

April 2019 in “Journal of the Endocrine Society”

A woman with severe hypothyroidism had a rare skin condition usually linked to a different thyroid disease.

An Unusual Case of Myxedema Coma

research An Unusual Case of Myxedema Coma

October 2024 in “Journal of the Endocrine Society”

Acute illnesses like sepsis can disrupt thyroid hormone balance without central hypothyroidism.

research Myxedema Coma and Acute Hepatopathy in a Dog with Severe Atherosclerosis

October 2021 in “Case Reports in Veterinary Medicine”

The dog died from myxedema coma linked to severe atherosclerosis and thyroid issues.

research Lichen myxedematosus in a patient with hepatocellular carcinoma

16 citations , August 2000 in “British Journal of Dermatology”

Removing the liver tumor improved the patient's skin condition and hair growth.

research Pretibial Myxedema with Graves' Disease: A Case Report and Review of Japanese Literature

12 citations , April 1998 in “The Journal of Dermatology”

Pretibial myxedema can occur with Graves' disease, showing skin changes like waxy plaques and swelling.

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