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research Ion Sequential Therapy Aligned With Pathological Changes Enhances Cardiac Function After Myocardial Infarction

September 2024

This study reports that in a rat model of myocardial infarction, Zn-Cu ion sequential therapy improved cardiac function and cardiomyocyte metabolic activity by precisely regulating ion concentrations and maintaining elevated levels of the Per2 protein, important for cellular repair.

Anti-Androgenic Therapy with Finasteride Improves Cardiac Function, Attenuates Remodeling, and Reverts Pathologic Gene Expression After Myocardial Infarction in Mice

research Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice

13 citations , August 2018 in “Journal of Molecular and Cellular Cardiology”

This study demonstrated that finasteride treatment reduced cardiac dysfunction and hypertrophic remodeling in mice after myocardial infarction, suggesting potential as a therapeutic strategy for heart failure.

Corrigendum to 'Anti-Androgenic Therapy with Finasteride Improves Cardiac Function, Attenuates Remodeling and Reverts Pathologic Gene-Expression After Myocardial Infarction in Mice'

research Corrigendum to “Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice” Journal of Molecular and Cellular Cardiology 122 (2018) 114–124

November 2018 in “Journal of Molecular and Cellular Cardiology”

This study found that finasteride improved cardiac function and reduced remodeling after myocardial infarction in mice.

Serum Dihydrotestosterone Levels Are Associated With Adverse Myocardial Remodeling in Patients With Severe Aortic Valve Stenosis Before and After Aortic Valve Replacement

research Serum dihydrotestosterone levels are associated with adverse myocardial remodeling in patients with severe aortic valve stenosis before and after aortic valve replacement

4 citations , October 2022 in “American journal of physiology. Heart and circulatory physiology”

This study found that in patients with severe aortic valve stenosis, higher serum dihydrotestosterone levels were associated with increased myocardial hypertrophy, fibrosis, and reduced left ventricular function.

research Cell Type-specific Functions of the Lysosomal Protease Cathepsin L in the Heart

56 citations , October 2007 in “Journal of Biological Chemistry”

This study concluded that dilated cardiomyopathy in Ctsl-deficient mice is mainly due to the lack of cathepsin L in cardiomyocytes, with additional heart stress from the fur defect.

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community Topical minoxidil can still kill cats even when the owner is “careful.”

in Minoxidil 259 upvotes 1 month ago

Topical minoxidil can be dangerous to cats, even with accidental exposure, and users should be cautious to prevent poisoning. Proper precautions, like washing hands and preventing cats from licking treated areas, are essential to minimize risk.

community The Biggest Concern That I Have For Oral Minoxidil: Cardiac Hypertrophy

26 upvotes 3 years ago

Oral minoxidil can cause serious heart issues like cardiac hypertrophy and arrhythmias, prompting some users to reduce dosage or switch to topical treatments. Despite significant hair regrowth, side effects such as shortness of breath and chest pains are common concerns.

community Male pattern baldness is not cosmetic.

224 upvotes 9 months ago

Male pattern baldness is linked to health risks and should be treated medically. Finasteride is effective and should be insurance-covered.

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