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Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function

research Glucocorticoid Receptor Mutants Demonstrate Increased Motility Inside the Nucleus of Living Cells: Time of Fluorescence Recovery After Photobleaching Is an Integrated Measure of Receptor Function

31 citations, July 2004 in “Molecular Medicine”

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

High-Resolution Structures of Mutants Affecting Access to the Ligand-Binding Cavity of Human Lipocalin-Type Prostaglandin D Synthase

research High-Resolution Structures of Mutants Affecting Access to the Ligand-Binding Cavity of Human Lipocalin-Type Prostaglandin D Synthase

5 citations, July 2014 in “Acta Crystallographica Section D-biological Crystallography”

Mutations in the enzyme don't significantly change how it binds to its specific substances.

research Functional Characterization of Soybean Strigolactone Biosynthesis and Signaling Genes in Arabidopsis MAX Mutants and GmMAX3 in Soybean Nodulation

43 citations, December 2017 in “BMC Plant Biology”

GmMAX3b gene in soybeans boosts nodulation and affects hormone levels.

research Cross-Linked Features of Mouse Pelage Hair Resistant to Detergent Extraction

February 1999 in “The anatomical record”

Two mouse mutants have defective hair cuticle cross-linking.

research Differential Expression of Keratin and Keratin-Associated Proteins Linked with Hair Loss in Spontaneously Mutated Inbred Mice

July 2024 in “bioRxiv (Cold Spring Harbor Laboratory)”

Hair loss in certain mice is linked to changes in keratin-related genes.

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Community Join

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community 5.5 months (Min 2 times /fin 1.25 1 time) daily //derma 1 every week some supplement and Sometimes I use ketoquinazole shampoo The real results from the beginning of the tenth image. 23 y

in Progress Pictures 396 upvotes 6 months ago

The user experienced improved hair growth using Minoxidil twice daily, finasteride 1.25mg once daily, weekly dermarolling, supplements, and occasional ketoconazole shampoo for 5.5 months, but noticed hair shedding again after switching types of Minoxidil. Despite returning to the original Minoxidil, the user's hair condition worsened and shedding continued.

community 48M, 11 month progress, 1MG finasteride only

in Progress Pictures 627 upvotes 1 year ago

A 48-year-old man's 11-month progress using 1mg finasteride for hair loss treatment, with significant improvement and no side effects. Other users share their experiences, with some also seeing positive results, while others have not been as successful.

community Androgen degraders for hair loss

in Research/Science 60 upvotes 2 months ago

The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

community You guys are all doing it wrong. 7 days and $3.58 is all it takes.

in Satire 129 upvotes 3 months ago

This post and conversation are about mocking hair loss treatments, specifically Minoxidil, finasteride, and RU58841, with humorous and sarcastic comments. The satire suggests absurd methods and results, highlighting skepticism about these treatments.

community 11 month hair update.. The minoxidil and finasteride really work miracles 😳😳😳

in Progress Pictures 864 upvotes 3 years ago

User "Jordan_cadagan" shares 11-month progress using minoxidil and finasteride for hair growth, with impressive results. Users discuss application methods, ice baths possibly helping, and daily dosages.

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