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research Transgenic mice display hair loss and regrowth overexpressing mutant Hr gene

January 2017 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu”

This study found that in transgenic mice overexpressing a mutant hairless gene, changes in its expression affected hair loss and regrowth, implicating the gene's role in hair follicle biology.

research The Effect of Hairless Mutant Gene on The Thymus and Skin Under The C_(57)BL/6 Genetic Background

January 2004 in “Laboratory Animal Science and Administration”

This study found that the hairless mutant gene in C 57BL/6 mice affects the hair follicle cycle and leads to early thymus degeneration and distinct skin changes.

research The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation

68 citations , December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study suggests a regulatory model where HOXC13 activates Foxn1, affecting hair and nail differentiation, supported by similarities in Hoxc13(tm1Mrc) and Foxn1(nu) mice phenotypes and gene expression patterns.

Evidence That the Satin Hair Mutant Gene Foxq1 Is Among Multiple and Functionally Diverse Regulatory Targets for Hoxc13 During Hair Follicle Differentiation

research Evidence That the Satin Hair Mutant Gene Foxq1 Is among Multiple and Functionally Diverse Regulatory Targets for Hoxc13 during Hair Follicle Differentiation

65 citations , July 2006 in “Journal of biological chemistry/The Journal of biological chemistry”

This study found that overexpression of Hoxc13 in GC13 mouse models affects hair follicle differentiation by interacting with medulla-specific genes, particularly Foxq1, suggesting a regulatory pathway for medulla differentiation.

research Amelioration by Copper Supplementation of Mutant Gene Effects in the Crinkled Mouse

23 citations , August 1975 in “Experimental Biology and Medicine”

This study found that supplementing pregnant and lactating mice with high dietary copper improved survival and physical traits in mice carrying the crinkled mutation, suggesting copper's role in modulating gene expression.

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community King thutmose IV kept his hair for 7000 years, was he on finasteride?

in Satire 867 upvotes 9 months ago

King Thutmose IV's hair retention is humorously speculated to be due to treatments like finasteride, minoxidil, or other unconventional methods. The discussion includes jokes about genetics, ancient practices, and modern hair loss solutions.

community Is Elon on fin or dut? He made at least one transplant before

in Treatment 265 upvotes 1 year ago

Elon Musk likely had at least two hair transplants and uses finasteride or dutasteride to maintain his hair. He may also use a hair system or prosthetic hair.

community Androgen degraders for hair loss

61 upvotes 2 years ago

The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community What was your "fuck it, I'm starting Fin/Dut" moment?

in Finasteride/Dutasteride 77 upvotes 1 year ago

People discussed starting hair loss treatments like finasteride, dutasteride, and minoxidil due to personal experiences or comments about their hair loss. Some reported positive results, while others mentioned side effects or switching treatments.

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Hair System Specialist
Jane Genesi
Marlton, PA, United States

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Jane Genesi