9 citations
,
May 2019 in “Experimental Cell Research” This study found that Hedgehog signaling likely contributes to cervical carcinogenesis, and while itraconazole reduced growth in mice, it did so through pathways other than inhibiting Hedgehog signaling.
2 citations
,
August 2022 in “Viruses” This study found that cutaneous squamous cell carcinomas in mice infected with murine papillomavirus preferentially arise from Lgr5+ progenitor cells, while squamous cell dysplasia does not.
19 citations
,
June 2008 in “Journal of Investigative Dermatology” This study found that transgenic mice with expression of HPV16 E6/E7 oncogenes showed improved ear tissue regeneration, including hair follicles and cartilage, without tumor formation.
112 citations
,
May 2020 in “Nature Communications” This study found that cardiac fibroblasts significantly enhance the maturation of neonatal mouse and human embryonic stem cell-derived cardiomyocytes, suggesting a pivotal role in postnatal heart development and disease.
14 citations
,
January 2016 in “Experimental and molecular pathology” This study found that T cell-deficient mice developed distinct papilloma phenotypes after MmuPV1 infection, and hyperimmune sera transfer could prevent this infection.