106 citations
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April 1986 in “British Journal of Dermatology” This study found that dermal papilla cells from human hair follicles form multi-layered aggregates when cultured in vitro, contrasting with the monolayer growth of dermal fibroblasts.
August 2023 in “Micromachines” In this study, researchers developed a multilayered gel bead culture model using a microgel-spotting device, successfully mimicking the early development of skin appendages and supporting in vitro hair follicle regeneration with structures resembling native hair follicles.
September 2017 in “Journal of Investigative Dermatology” This study found that hyaluronic acid increased the size and cell proliferation of mixed aggregates in a 3D culture model, indicating its role in human hair follicle germ-like structure formation without enhancing dermal papilla cell markers.
24 citations
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January 1989 This research discusses the function and culture of human dermal papilla cells, noting their unique in vitro characteristics and the ongoing efforts to understand their role in inducing hair growth.
1 citations
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July 2025 in “Barrier Immunity” This review synthesizes existing research on the multilayered defense system of the skin, highlighting how physical, chemical, immune, and microbial barriers work together to maintain skin health, with disruptions in one often leading to broader barrier dysfunctions.