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GlossaryMT-CO1 (MTCO1)

encodes a key enzyme subunit for cellular energy production

MT-CO1, also known as Mitochondrially Encoded Cytochrome C Oxidase I, is a gene found in mitochondrial DNA that encodes a key subunit of the enzyme cytochrome c oxidase. This enzyme is crucial for the electron transport chain, which is a series of reactions that produce energy in the form of ATP within cells. Mutations in MT-CO1 can affect cellular energy production and are associated with various mitochondrial disorders.

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A Novel Link Between Human Hair Follicle Neuroimmunology and Mitochondrial Biology: Substance P Increases Intrafollicular Oxidative Stress and Mitochondrial Biogenesis

research A Novel Link Between Human Hair Follicle Neuroimmunology and Mitochondrial Biology: Substance P Increases Intrafollicular Oxidative Stress and Mitochondrial Biogenesis

July 2022 in “Journal of Investigative Dermatology”

Substance P may contribute to hair loss by increasing oxidative stress and mitochondrial activity in hair follicles.

The Bacterial Metabolite, Butyrate, Prolongs Anagen and Promotes Autophagy, Mitochondrial Activity, Melanogenesis and Antimicrobial Peptide Production in Human Scalp Hair Follicles

research The Bacterial Metabolite, Butyrate, Prolongs Anagen and Promotes Autophagy, Mitochondrial Activity, Melanogenesis and Antimicrobial Peptide Production in Human Scalp Hair Follicles

November 2022 in “Journal of Investigative Dermatology”

Butyrate helps hair grow longer, improves hair cell health, increases pigment production, and boosts hair's natural defenses.

research Spontaneous Intrinsic Aging in Organ-Cultured Human Skin as a Novel Ex Vivo Assay to Test Anti-Aging Actives

November 2022 in “Journal of Investigative Dermatology”

The document concludes that a new method has been developed to test anti-aging substances on human skin, showing that these substances can reduce skin aging signs.

research Mitochondrial MPZL3 in the Inner Root Sheath Regulates Human Hair Follicle Cycling Ex Vivo

1 citations , July 2024 in “Journal of Investigative Dermatology”

MPZL3 protein affects hair growth cycles and could help manage hair loss.

research Hypothalamic–Pituitary–Thyroid Axis Hormones Stimulate Mitochondrial Function and Biogenesis in Human Hair Follicles

95 citations , August 2013 in “Journal of Investigative Dermatology”

HPT axis hormones boost mitochondrial function and growth in hair follicles, potentially aiding hair health.

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