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This review discusses the evidence for using oral medications to treat central serous chorioretinopathy, highlighting eplerenone as having the most support despite a lack of robust efficacy across studies.

In this study, a pregnant woman inadvertently exposed to spironolactone delivered a healthy male infant with normal genitalia, highlighting the need for more research on the safety of spironolactone and new-generation mineralocorticoid receptor antagonists during pregnancy.

This study found that overexpression of the mineralocorticoid receptor in a mouse model led to premature epidermal barrier development, keratinocyte apoptosis, and postnatal alopecia, indicating new roles for MR signaling in skin physiology.

This review discusses the role of the mineralocorticoid receptor in skin biology, highlighting its potential involvement in keratinocyte and hair physiology, and proposes it may affect the side effects of glucocorticoid use.

This study found no significant association between mineralocorticoid receptor antagonist therapy and mortality in patients with SARS-CoV-2 infection.