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Repurposing a Clinical Antimalarial for the Therapeutic Induction of Lethal ER Stress Targeting BRAF-Kinase Inhibitor-Resistant Malignant Melanoma

research Repurposing a Clinical Antimalarial for the Therapeutic Induction of Lethal ER Stress Targeting BRAF-Kinase Inhibitor-Resistant Malignant Melanoma

April 2016 in “Journal of Investigative Dermatology”

Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.

research Prostatic Cystic Hyperplasia in a Young Dog: Case Report

May 2023 in “MQRInvestigar”

A young dog with an enlarged prostate and cysts improved significantly after treatment and surgery.

research Imaging of Zinc Oxide Nanoparticle Penetration in Human Skin In Vitro and In Vivo

264 citations, January 2008 in “Journal of biomedical optics”

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

research A Peptide Derivative with Known Anti-Wrinkle Properties Identified as Potent Dipeptidylpeptidase-4 Inhibitor

April 2016 in “Journal of Investigative Dermatology”

A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.

research Impact of a Stimulating Cream Shampoo Treatment on the Penetration of Minoxidil Through Hair Follicles

April 2016 in “Journal of Investigative Dermatology”

Using a stimulating cream shampoo before applying Minoxidil helps it penetrate hair follicles better, enhancing its hair growth-promoting effect.

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Community Join

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community Nearing 3 Year Hair Journey 2021-2023

in Progress Pictures 113 upvotes 10 months ago

The user shared their nearly 3-year hair loss treatment journey, starting with minoxidil, then adding finasteride, nizoral shampoo, and microneedling, later incorporating oral minoxidil and RU58841, and recently switching to dutasteride. They are considering replacing RU58841 with pyrilutamide and are aware of the potential side effects of oral minoxidil on heart health.

community Question for Russians in this subreddit

in Product 1 upvotes 2 months ago

The user plans to switch to oral finasteride and oral minoxidil due to insufficient results from PRP, topical minoxidil, and mild DHT inhibitors. They seek advice on purchasing these medications from My.India, questioning its trustworthiness.

community Does whey protein and creatine aggravate hair loss?

in Research/Science 82 upvotes 11 months ago

The conversation discusses whether whey protein and creatine worsen hair loss. Some users report hair loss with creatine use, while others do not; opinions on whey protein's effects are mixed. Treatments mentioned include PRP, minoxidil, and finasteride.

community pyrilutamide phase 2 results right here, thanks to user Glaringbooch

in Chat 40 upvotes 2 years ago

Pyrilutamide, a new drug being tested to combat hair loss that has been found to perform comparably or better than finasteride and dutasteride in the initial 6 months of treatment with minimal reported side effects.

community DIY Dutasteride Mesotherapy....THE ULTIMATE EXPERIMENT WITH RESULTS! (UPDATED! MISSION COMPLETE)

in Finasteride/Dutasteride 37 upvotes 3 years ago

The post discusses a DIY Dutasteride Mesotherapy procedure for hair regrowth, supplemented with oral Minoxidil. The user describes the process, including preparation, equipment used, and initial results, expressing excitement for future outcomes.