June 2023 in “Journal of biological chemistry/The Journal of biological chemistry” This study on Sdr16c5/Sdr16c6-null mice found that inactivating these genes significantly increased Meibomian gland secretions and altered lipid profiles but had a subtle impact on sebogenesis, suggesting the genes control a bifurcation point in meibogenesis pathways.
24 citations
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July 2018 in “Stem cells” This study found that Runx1 in hair follicle stem cells modulates lipid metabolism, impacting membrane organization and enhancing signal transduction for cell proliferation in both normal and cancer epithelial cells.
47 citations
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May 2021 in “Polymers” This review surveys the chemical composition and various uses of jojoba oil in medicine and industry but presents no new clinical results.
May 2024 in “Journal of medicinal food” This review highlights jojoba oil's unique composition and its growing therapeutic applications, noting its antioxidant, anti-acne, antidiabetic, and antibacterial properties, as well as its use in various pharmaceutical formulations.
25 citations
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February 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, topical application of the SCD1 inhibitor XEN103 significantly reduced sebaceous gland size and number in mouse skin, suggesting potential local therapeutic effects for acne treatment without systemic side effects.